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P2Y(12) or P2Y(1) inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions()
Determination of the patient-specific response to antiplatelet agents facilitates proper dosing for both acute and chronic prophylaxis. “Closed” systems (with or without flow) may fail to predict pharmacological potency in situations where platelets rapidly accumulate under flow conditions at a site...
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| Publicado no: | Integr Biol (Camb) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441395/ https://ncbi.nlm.nih.gov/pubmed/20473398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b919728a |
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