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Pairwise Agonist Scanning of human platelets reveals the high-dimensional calcium response to combinatorial mediators of thrombosis

Patient-specific prediction of cellular response to multiple stimuli is central to evaluating clinical risk, disease progression, and response to therapy. We deployed Pairwise Agonist Scanning (PAS) to measure calcium signaling of human platelets in EDTA-treated plasma exposed to 6 different agonist...

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Detalles Bibliográficos
Main Authors: Chatterjee, Manash S., Purvis, Jeremy E., Brass, Lawrence F., Diamond, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010846/
https://ncbi.nlm.nih.gov/pubmed/20562863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1642
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