TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements

BACKGROUND: TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown. We now hypothesized that cytokine secretion from TREK-1-deficient AECs was regulated...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Schwingshackl, Andreas, Roan, Esra, Teng, Bin, Waters, Christopher M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441361/
https://ncbi.nlm.nih.gov/pubmed/26001192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126781
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