Regulation of Monocyte Chemotactic Protein-1 secretion by the Two-Pore-Domain Potassium (K2P) channel TREK-1 in human alveolar epithelial cells

We recently proposed a role for the 2-pore-domain K(+) (K2P) channel TREK-1 in the regulation of cytokine release from alveolar epithelial cells (AECs) by demonstrating decreased IL-6 secretion from TREK-1 deficient cells, but the effects of altered TREK-1 expression on other inflammatory mediators...

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Bibliografiske detaljer
Main Authors: Schwingshackl, Andreas, Teng, Bin, Ghosh, Manik, Waters, Christopher M
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745440/
https://ncbi.nlm.nih.gov/pubmed/23977412
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