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Dissection of an antibody-catalyzed reaction.

Antibody 43C9 accelerates the hydrolysis of a p-nitroanilide by a factor of 2.5 x 10(5) over the background rate in addition to catalyzing the hydrolysis of a series of aromatic esters. Since this represents one of the largest rate accelerations achieved with an antibody, we have undertaken a series...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Stewart, J D, Krebs, J F, Siuzdak, G, Berdis, A J, Smithrud, D B, Benkovic, S J
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44409/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7404
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