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Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling

Multiple studies show that chronic lymphocytic leukemia (CLL) cells are heavily dependent on their microenvironment for survival. Communication between CLL cells and the microenvironment is mediated through direct cell contact, soluble factors, and extracellular vesicles. Exosomes are small particle...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Yeh, Yuh-Ying, Ozer, Hatice Gulcin, Lehman, Amy M., Maddocks, Kami, Yu, Lianbo, Johnson, Amy J., Byrd, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440883/
https://ncbi.nlm.nih.gov/pubmed/25833959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-618470
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