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Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling

Multiple studies show that chronic lymphocytic leukemia (CLL) cells are heavily dependent on their microenvironment for survival. Communication between CLL cells and the microenvironment is mediated through direct cell contact, soluble factors, and extracellular vesicles. Exosomes are small particle...

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Pubblicato in:Blood
Autori principali: Yeh, Yuh-Ying, Ozer, Hatice Gulcin, Lehman, Amy M., Maddocks, Kami, Yu, Lianbo, Johnson, Amy J., Byrd, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440883/
https://ncbi.nlm.nih.gov/pubmed/25833959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-618470
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