Influence of Different Antioxidants on X-Ray Induced DNA Double-Strand Breaks (DSBs) Using γ-H2AX Immunofluorescence Microscopy in a Preliminary Study

BACKGROUND: Radiation exposure occurs in X-ray guided interventional procedures or computed tomography (CT) and γ-H2AX-foci are recognized to represent DNA double-strand breaks (DSBs) as a biomarker for radiation induced damage. Antioxidants may reduce the induction of γ-H2AX-foci by binding free ra...

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Publicado no:PLoS One
Main Authors: Brand, Michael, Sommer, Matthias, Ellmann, Stephan, Wuest, Wolfgang, May, Matthias S., Eller, Achim, Vogt, Sabine, Lell, Michael M., Kuefner, Michael A., Uder, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440758/
https://ncbi.nlm.nih.gov/pubmed/25996998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127142
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