S1P-Dependent Trafficking of Intracellular Yersinia pestis through Lymph Nodes Establishes Buboes and Systemic Infection

Pathologically swollen lymph nodes (LNs), or buboes, characterize Yersinia pestis infection, yet how they form and function is unknown. We report that colonization of the draining LN (dLN) occurred due to trafficking of infected dendritic cells and monocytes in temporally distinct waves in response...

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Bibliographic Details
Published in:Immunity
Main Authors: St. John, Ashley L., Ang, W.X. Gladys, Huang, Min-Nung, Kunder, Christian A., Chan, Elizabeth W., Gunn, Michael D., Abraham, Soman N.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440548/
https://ncbi.nlm.nih.gov/pubmed/25238098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.07.013
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