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Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes

When draining lymph nodes become infected by Yersinia pestis (Y. pestis), a massive influx of phagocytic cells occurs, resulting in distended and necrotic structures known as buboes. The bubonic stage of the Y. pestis life cycle precedes septicemia, which is facilitated by trafficking of infected mo...

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Arifuzzaman, Mohammad, Ang, W.X. Gladys, Choi, Hae Woong, Nilles, Matthew L., St. John, Ashley L., Abraham, Soman N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237236/
https://ncbi.nlm.nih.gov/pubmed/30232285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122188
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