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Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes

When draining lymph nodes become infected by Yersinia pestis (Y. pestis), a massive influx of phagocytic cells occurs, resulting in distended and necrotic structures known as buboes. The bubonic stage of the Y. pestis life cycle precedes septicemia, which is facilitated by trafficking of infected mo...

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Publicat a:JCI Insight
Autors principals: Arifuzzaman, Mohammad, Ang, W.X. Gladys, Choi, Hae Woong, Nilles, Matthew L., St. John, Ashley L., Abraham, Soman N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237236/
https://ncbi.nlm.nih.gov/pubmed/30232285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122188
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