Transcriptomic and Innate Immune Responses to Yersinia pestis in the Lymph Node during Bubonic Plague

A delayed inflammatory response is a prominent feature of infection with Yersinia pestis, the agent of bubonic and pneumonic plague. Using a rat model of bubonic plague, we examined lymph node histopathology, transcriptome, and extracellular cytokine levels to broadly characterize the kinetics and e...

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Main Authors: Comer, Jason E., Sturdevant, Daniel E., Carmody, Aaron B., Virtaneva, Kimmo, Gardner, Donald, Long, Dan, Rosenke, Rebecca, Porcella, Stephen F., Hinnebusch, B. Joseph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981309/
https://ncbi.nlm.nih.gov/pubmed/20876291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00256-10
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