A Two-Step Pretargeted Nanotherapy for CD20 Crosslinking May Achieve Superior Anti-Lymphoma Efficacy to Rituximab

The use of rituximab, an anti-CD20 mAb, in combination with chemotherapy is the current standard for the treatment of B-cell lymphomas. However, because of a significant number of treatment failures, there is a demand for new, improved therapeutics. Here, we designed a nanomedicine that crosslinks C...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Chu, Te-Wei, Zhang, Rui, Yang, Jiyuan, Chao, Mark P., Shami, Paul J., Kopeček, Jindřich
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440441/
https://ncbi.nlm.nih.gov/pubmed/26000056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.12040
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