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QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology
The mitochondrial contact site and cristae junction (CJ) organizing system (MICOS) dynamically regulate mitochondrial membrane architecture. Through systematic proteomic analysis of human MICOS, we identified QIL1 (C19orf70) as a novel conserved MICOS subunit. QIL1 depletion disrupted CJ structure i...
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Publicado no: | eLife |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439739/ https://ncbi.nlm.nih.gov/pubmed/25997101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06265 |
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