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Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.

Cyclosporin A, FK-506, and rapamycin are immunosuppressants often used as pharmacological probes to study lymphocyte activation and physiological cell death (PCD). Because cyclosporin A and FK-506 are known to prevent PCD in T-cell hybridomas and thymocytes, we used these reagents, as well as rapamy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gottschalk, A R, Boise, L H, Thompson, C B, Quintáns, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC44397/
https://ncbi.nlm.nih.gov/pubmed/7518929
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