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Bcl-X(L), but not Bcl-2, can protect human B-lymphoma cell lines from parthenolide-induced apoptosis

In this report, we investigated the effects of the natural product parthenolide on human B-lymphoma cell lines. We show that parthenolide inhibited NF-κB transcription factor c-Rel (REL). In addition, the sensitivity of several human B-lymphoma cell lines to parthenolide-induced apoptosis inversely...

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Detalhes bibliográficos
Main Authors: Yeo, Alan T., Porco, John A., Gilmore, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288124/
https://ncbi.nlm.nih.gov/pubmed/22155272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.11.035
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