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Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: A computational analysis
Insulin secretory responses to nutrient stimuli and hormonal modulators in pancreatic beta-cells are controlled by a variety of secondary messengers. We have analyzed numerous mechanisms responsible for regulated exocytosis in these cells and present an integrated mathematical model of cytosolic Ca(...
Kaydedildi:
| Yayımlandı: | Prog Biophys Mol Biol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439405/ https://ncbi.nlm.nih.gov/pubmed/21920379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2011.09.001 |
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