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Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: A computational analysis
Insulin secretory responses to nutrient stimuli and hormonal modulators in pancreatic beta-cells are controlled by a variety of secondary messengers. We have analyzed numerous mechanisms responsible for regulated exocytosis in these cells and present an integrated mathematical model of cytosolic Ca(...
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| Publicat a: | Prog Biophys Mol Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439405/ https://ncbi.nlm.nih.gov/pubmed/21920379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2011.09.001 |
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