Loading...

Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B

BACKGROUND & AIMS: New therapies for chronic hepatitis B (CHB) are urgently needed since current treatments rarely lead to cure. We evaluated whether the oral small molecule toll-like receptor (TLR7) agonist GS-9620 could induce durable anti-viral efficacy in woodchucks chronically infected with...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Hepatol
Main Authors: Menne, Stephan, Tumas, Daniel B., Liu, Katherine H., Thampi, Linta, AlDeghaither, Dalal, Baldwin, Betty H., Bellezza, Christine A., Cote, Paul J., Zheng, Jim, Halcomb, Randall, Fosdick, Abigail, Fletcher, Simon P., Daffis, Stephane, Li, Li, Yue, Peng, Wolfgang, Grushenka H. I., Tennant, Bud C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439359/
https://ncbi.nlm.nih.gov/pubmed/25559326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.12.026
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!