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Innate lymphoid cell development requires TOX-dependent generation of a common ILC progenitor

Diverse innate lymphoid cell (ILC) subtypes have been defined, based on effector function and transcription factor expression. ILCs derive from common lymphoid progenitors, although the transcriptional pathways leading to ILC lineage specification remain poorly characterized. Here we demonstrate tha...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Seehus, Corey R., Aliahmad, Parinaz, de la Torre, Brian, Iliev, Iliyan D., Spurka, Lindsay, Funari, Vincent A., Kaye, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439271/
https://ncbi.nlm.nih.gov/pubmed/25915732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3168
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