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Development of all CD4 T lineages requires nuclear factor TOX

CD8(+) cytotoxic and CD4(+) helper/inducer T cells develop from common thymocyte precursors that express both CD4 and CD8 molecules. Upon T cell receptor signaling, these cells initiate a differentiation program that includes complex changes in CD4 and CD8 expression, allowing identification of tran...

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Detalhes bibliográficos
Main Authors: Aliahmad, Parinaz, Kaye, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234360/
https://ncbi.nlm.nih.gov/pubmed/18195075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071944
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