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TOX is required for development of the CD4 T cell lineage gene program

The factors that regulate thymic development of the CD4(+) T cell gene program remain poorly defined. The transcriptional regulator ThPOK is a dominant factor in CD4(+) T cell development, which functions primarily to repress the CD8 lineage fate. Previously, we showed that nuclear protein TOX is al...

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Bibliografske podrobnosti
Main Authors: Aliahmad, Parinaz, Kadavallore, Asha, de la Torre, Brian, Kappes, Dietmar, Kaye, Jonathan
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221881/
https://ncbi.nlm.nih.gov/pubmed/22021617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101474
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