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TOX is required for development of the CD4 T cell lineage gene program
The factors that regulate thymic development of the CD4(+) T cell gene program remain poorly defined. The transcriptional regulator ThPOK is a dominant factor in CD4(+) T cell development, which functions primarily to repress the CD8 lineage fate. Previously, we showed that nuclear protein TOX is al...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221881/ https://ncbi.nlm.nih.gov/pubmed/22021617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101474 |
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