Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells

Epidermal growth factor receptor variant III (EGFRvIII) has been associated with glioma stemness, but the direct molecular mechanism linking the two is largely unknown. Here, we show that EGFRvIII induces the expression and secretion of pigment epithelium-derived factor (PEDF) via activation of sign...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Yin, Jinlong, Park, Gunwoo, Kim, Tae Hoon, Hong, Jun Hee, Kim, Youn-Jae, Jin, Xiong, Kang, Sangjo, Jung, Ji-Eun, Kim, Jeong-Yub, Yun, Hyeongsun, Lee, Jeong Eun, Kim, Minkyung, Chung, Junho, Kim, Hyunggee, Nakano, Ichiro, Gwak, Ho-Shin, Yoo, Heon, Yoo, Byong Chul, Kim, Jong Heon, Hur, Eun-Mi, Lee, Jeongwu, Lee, Seung-Hoon, Park, Myung-Jin, Park, Jong Bae
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439169/
https://ncbi.nlm.nih.gov/pubmed/25992628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002152
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados