Thymic Stromal Lymphopoietin Is Up-Regulated in the Skin of Patients With Systemic Sclerosis and Induces Profibrotic Genes and Intracellular Signaling That Overlap With Those Induced by Interleukin-13 and Transforming Growth Factor β

OBJECTIVE: To explore the expression of thymic stromal lymphopoietin (TSLP) in patients with diffuse cutaneous systemic sclerosis (dcSSc) and compare its effects in vivo and in vitro with those of interleukin-13 (IL-13) and transforming growth factor β (TGFβ). METHODS: Skin biopsy specimens from pat...

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Vydáno v:Arthritis Rheum
Hlavní autoři: Christmann, Romy B., Mathes, Allison, Affandi, Alsya J., Padilla, Cristina, Nazari, Banafsheh, Bujor, Andreea M., Stifano, Giuseppina, Lafyatis, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437575/
https://ncbi.nlm.nih.gov/pubmed/23335246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37859
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