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A mathematical model quantifies proliferation and motility effects of TGF-β on cancer cells

Transforming growth factor (TGF)-β is known to have properties of both a tumour suppressor and a tumour promoter. While it inhibits cell proliferation, it also increases cell motility and decreases cell–cell adhesion. Coupling mathematical modelling and experiments, we investigate the growth and mot...

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Dettagli Bibliografici
Pubblicato in:Comput Math Methods Med
Autori principali: Wang, Shizhen Emily, Hinow, Peter, Bryce, Nicole, Weaver, Alissa M., Estrada, Lourdes, Arteaga, Carlos L., Webb, Glenn F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437567/
https://ncbi.nlm.nih.gov/pubmed/26000030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17486700802171993
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