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Bitter Taste Receptors on Airway Smooth Muscle as Targets for Novel Bronchodilators

INTRODUCTION: There is an unmet need for a new class of direct bronchodilators for the treatment of asthma and chronic obstructive lung disease. Unexpectedly, bitter taste receptors (TAS2Rs) have been localized on airway smooth muscle and when activated cause marked smooth muscle relaxation via a me...

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Библиографические подробности
Опубликовано в: :Expert Opin Ther Targets
Главный автор: Liggett, Stephen B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437536/
https://ncbi.nlm.nih.gov/pubmed/23577615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.782395
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