The pluripotency factor NANOG promotes the formation of squamous cell carcinomas

NANOG is a key pluripotency factor in embryonic stem cells that is frequently expressed in squamous cell carcinomas (SCCs). However, a direct link between NANOG and SCCs remains to be established. Here, we show that inducible overexpression of NANOG in mouse skin epithelia favours the malignant conv...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Palla, Adelaida R., Piazzolla, Daniela, Alcazar, Noelia, Cañamero, Marta, Graña, Osvaldo, Gómez-López, Gonzalo, Dominguez, Orlando, Dueñas, Marta, Paramio, Jesús M., Serrano, Manuel
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437308/
https://ncbi.nlm.nih.gov/pubmed/25988972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10205
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