Glutamine and alanyl-glutamine promote crypt expansion and mTOR signaling in murine enteroids

l-Glutamine (Gln) is a key metabolic fuel for intestinal epithelial cell proliferation and survival and may be conditionally essential for gut homeostasis during catabolic states. We show that l-alanyl-l-glutamine (Ala-Gln), a stable Gln dipeptide, protects mice against jejunal crypt depletion in th...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Gastrointest Liver Physiol
Egile Nagusiak: Moore, Sean R., Guedes, Marjorie M., Costa, Tie B., Vallance, Jefferson, Maier, Elizabeth A., Betz, Kristina J., Aihara, Eitaro, Mahe, Maxime M., Lima, Aldo A. M., Oriá, Reinaldo B., Shroyer, Noah F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Call for Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437023/
https://ncbi.nlm.nih.gov/pubmed/25792564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00422.2014
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