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Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages

Inflammasomes are cytosolic protein complexes that promote the cleavage of caspase-1, which leads to the maturation and secretion of proinflammatory cytokines, including interleukin-1β (IL-1β) and IL-18. Among the known inflammasomes, the nucleotide-binding domain, leucine-rich-containing family, py...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Jung, Sung-Soo, Moon, Jong-Seok, Xu, Jin-Fu, Ifedigbo, Emeka, Ryter, Stefan W., Choi, Augustine M. K., Nakahira, Kiichi
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437010/
https://ncbi.nlm.nih.gov/pubmed/25770182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00400.2014
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