Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt

The collecting system of the kidney develops from the ureteric bud (UB), which undergoes branching morphogenesis, a process regulated by multiple factors, including integrin–extracellular matrix interactions. The laminin (LM)-binding integrin α3β1 is crucial for this developmental program; however,...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Yazlovitskaya, Eugenia M., Tseng, Hui-Yuan, Viquez, Olga, Tu, Tianxiang, Mernaugh, Glenda, McKee, Karen K., Riggins, Karen, Quaranta, Vito, Pathak, Amrita, Carter, Bruce D., Yurchenco, Peter, Sonnenberg, Arnoud, Böttcher, Ralph T., Pozzi, Ambra, Zent, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436831/
https://ncbi.nlm.nih.gov/pubmed/25808491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1203
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