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Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau

Alzheimer’s disease (AD) is characterized by extracellular amyloid β (Aβ) deposition and intracellular tau aggregation. Many studies have indicated some association between these processes, but it remains unknown how the two pathologies are linked. In this study, we investigated whether expression o...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Takahashi, Muneaki, Miyata, Haruka, Kametani, Fuyuki, Nonaka, Takashi, Akiyama, Haruhiko, Hisanaga, Shin-ichi, Hasegawa, Masato
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436700/
https://ncbi.nlm.nih.gov/pubmed/25869641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1415-2
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