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Role of six single nucleotide polymorphisms, risk factors in coronary disease, in OLR1 alternative splicing
The OLR1 gene encodes the oxidized low-density lipoprotein receptor (LOX-1), which is responsible for the cellular uptake of oxidized LDL (Ox-LDL), foam cell formation in atheroma plaques and atherosclerotic plaque rupture. Alternative splicing (AS) of OLR1 exon 5 generates two protein isoforms with...
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| Pubblicato in: | RNA |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4436670/ https://ncbi.nlm.nih.gov/pubmed/25904137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.049890.115 |
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