Germline TP53 mutational spectrum in French Canadians with breast cancer

BACKGROUND: Specific germline mutations in the hereditary breast-ovarian cancer susceptibility (HBC/HBOC) genes, BRCA1, BRCA2 and PALB2, have been shown to recur in French Canadians of Quebec, Canada, and this has been attributed to common ancestors. Germline TP53 mutation carriers are known to segr...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Arcand, Suzanna L, Akbari, Mohammed R, Mes-Masson, Anne-Marie, Provencher, Diane, Foulkes, William D, Narod, Steven A, Tonin, Patricia N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436120/
https://ncbi.nlm.nih.gov/pubmed/25925845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0169-y
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