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Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families.

We have identified four mutations in each of the breast cancer-susceptibility genes, BRCA1 and BRCA2, in French Canadian breast cancer and breast/ovarian cancer families from Quebec. To identify founder effects, we examined independently ascertained French Canadian cancer families for the distributi...

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Библиографические подробности
Главные авторы: Tonin, P N, Mes-Masson, A M, Futreal, P A, Morgan, K, Mahon, M, Foulkes, W D, Cole, D E, Provencher, D, Ghadirian, P, Narod, S A
Формат: Artigo
Язык:Inglês
Опубликовано: 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377544/
https://ncbi.nlm.nih.gov/pubmed/9792861
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