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Double PALB2 and BRCA1/BRCA2 mutation carriers are rare in breast cancer and breast-ovarian cancer syndrome families from the French Canadian founder population

French Canadian families with breast cancer and breast-ovarian cancer syndrome harbor specific BRCA1, BRCA2 and PALB2 germline mutations, which have been attributed to common founders. Mutations in these genes confer an increased risk to breast and ovarian cancers, and have been identified to play a...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: ANCOT, FRÉDÉRIC, ARCAND, SUZANNA L., MES-MASSON, ANNE-MARIE, PROVENCHER, DIANE M., TONIN, PATRICIA N.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473670/
https://ncbi.nlm.nih.gov/pubmed/26137147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3123
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