Modulation of HIV-1 Replication by a Novel RhoA Effector Activity

The RhoA GTPase is involved in regulating actin cytoskeletal organization, gene expression, cell proliferation, and survival. We report here that p115-RhoGEF, a specific guanine nucleotide exchange factor (GEF) and activator of RhoA, modulates HIV-1 replication. Ectopic expression of p115-RhoGEF or...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Wang, Liping, Zhang, Hangchun, Solski, Patricia A., Hart, Matthew J., Der, Channing J., Su, Lishan
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435950/
https://ncbi.nlm.nih.gov/pubmed/10799900
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