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Modulation of NFAT-dependent gene expression by the RhoA signaling pathway in T cells
We have reported previously that p115Rho guanine nucleotide exchange factor, its upstream activator Gα13, and its effector RhoA are able to inhibit HIV-1 replication. Here, we show that RhoA is able to inhibit HIV-1 gene expression through the NFAT-binding site in the HIV long-terminal repeat. Const...
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| Publicado en: | J Leukoc Biol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418492/ https://ncbi.nlm.nih.gov/pubmed/17502338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0206120 |
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