Llwytho...

Modulation of NFAT-dependent gene expression by the RhoA signaling pathway in T cells

We have reported previously that p115Rho guanine nucleotide exchange factor, its upstream activator Gα13, and its effector RhoA are able to inhibit HIV-1 replication. Here, we show that RhoA is able to inhibit HIV-1 gene expression through the NFAT-binding site in the HIV long-terminal repeat. Const...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Leukoc Biol
Prif Awduron: Helms, Whitney S., Jeffrey, Jerry L., Holmes, Derek A., Townsend, Michael B., Clipstone, Neil A., Su, Lishan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418492/
https://ncbi.nlm.nih.gov/pubmed/17502338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0206120
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