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Induction of MHC Class I Expression on Immature Thymocytes in HIV-1-Infected SCID-hu Thy/Liv Mice: Evidence of Indirect Mechanisms()

The SCID-hu Thy/Liv mouse and human fetal thymic organ culture (HF-TOC) models have been used to explore the pathophysiologic mechanisms of HIV-1 infection in the thymus. We report here that HIV-1 infection of the SCID-hu Thy/Liv mouse leads to the induction of MHC class I (MHCI) expression on CD4(+...

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Publicado en:J Immunol
Main Authors: Kovalev, Grigoriy, Duus, Karen, Wang, Liping, Lee, Robert, Bonyhadi, Mark, Ho, David, McCune, Joseph M., Kaneshima, Hideto, Su, Lishan
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435947/
https://ncbi.nlm.nih.gov/pubmed/10358212
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