The specificity and topology of chromatin interaction pathways in yeast

Packaging of DNA into chromatin has a profound impact on gene expression. To understand how changes in chromatin influence transcription, we analyzed 165 mutants of chromatin machinery components in Saccharomyces cerevisiae. mRNA expression patterns change in 80% of mutants, always with specific eff...

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Publicat a:Mol Cell
Autors principals: Lenstra, Tineke L., Benschop, Joris J., Kim, TaeSoo, Schulze, Julia M., Brabers, Nathalie A.C.H., Margaritis, Thanasis, van de Pasch, Loes A.L., van Heesch, Sebastiaan A.A.C., Brok, Mariel O., Koerkamp, Marian J.A. Groot, Ko, Cheuk, van Leenen, Dik, Sameith, Katrin, van Hooff, Sander R., Lijnzaad, Philip, Kemmeren, Patrick, Hentrich, Thomas, Kobor, Michael S., Buratowski, Stephen, Holstege, Frank C.P.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435841/
https://ncbi.nlm.nih.gov/pubmed/21596317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.026
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