Exploratory Analysis of Glyburide as a Novel Therapy for Preventing Brain Swelling

BACKGROUND: Malignant infarction is characterized by the formation of cerebral edema, and medical treatment is limited. Preclinical data suggest that glyburide, an inhibitor of SUR1-TRPM4, is effective in preventing edema. We previously reported feasibility of the GAMES-Pilot study, a two-center pro...

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Bibliografiset tiedot
Julkaisussa:Neurocrit Care
Päätekijät: Sheth, Kevin N., Kimberly, W. Taylor, Elm, Jordan J., Kent, Thomas A., Yoo, Albert J., Thomalla, Götz, Campbell, Bruce, Donnan, Geoffrey A., Davis, Stephen M., Albers, Gregory W., Jacobson, Sven, del Zoppo, Gregory, Simard, J. Marc, Stern, Barney J., Mandava, Pitchaiah
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435684/
https://ncbi.nlm.nih.gov/pubmed/24671831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-014-9970-2
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