Exploratory Analysis of Glyburide as a Novel Therapy for Preventing Brain Swelling

BACKGROUND: Malignant infarction is characterized by the formation of cerebral edema, and medical treatment is limited. Preclinical data suggest that glyburide, an inhibitor of SUR1-TRPM4, is effective in preventing edema. We previously reported feasibility of the GAMES-Pilot study, a two-center pro...

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Detalhes bibliográficos
Publicado no:Neurocrit Care
Main Authors: Sheth, Kevin N., Kimberly, W. Taylor, Elm, Jordan J., Kent, Thomas A., Yoo, Albert J., Thomalla, Götz, Campbell, Bruce, Donnan, Geoffrey A., Davis, Stephen M., Albers, Gregory W., Jacobson, Sven, del Zoppo, Gregory, Simard, J. Marc, Stern, Barney J., Mandava, Pitchaiah
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435684/
https://ncbi.nlm.nih.gov/pubmed/24671831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-014-9970-2
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