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Exploratory Analysis of Glyburide as a Novel Therapy for Preventing Brain Swelling

BACKGROUND: Malignant infarction is characterized by the formation of cerebral edema, and medical treatment is limited. Preclinical data suggest that glyburide, an inhibitor of SUR1-TRPM4, is effective in preventing edema. We previously reported feasibility of the GAMES-Pilot study, a two-center pro...

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Bibliographische Detailangaben
Veröffentlicht in:Neurocrit Care
Hauptverfasser: Sheth, Kevin N., Kimberly, W. Taylor, Elm, Jordan J., Kent, Thomas A., Yoo, Albert J., Thomalla, Götz, Campbell, Bruce, Donnan, Geoffrey A., Davis, Stephen M., Albers, Gregory W., Jacobson, Sven, del Zoppo, Gregory, Simard, J. Marc, Stern, Barney J., Mandava, Pitchaiah
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435684/
https://ncbi.nlm.nih.gov/pubmed/24671831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-014-9970-2
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