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Human Data Supporting Glyburide in Ischemic Stroke
The SUR1-TRPM4 channel is a critical determinant of edema and hemorrhagic transformation after focal ischemia. Blockade of this channel by the small molecule glyburide results in improved survival and neurological outcome in multiple preclinical models of ischemic stroke. A robust, compelling body o...
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| Publicado no: | Acta Neurochir Suppl |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5189719/ https://ncbi.nlm.nih.gov/pubmed/26463916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-18497-5_3 |
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