Altered Versican Cleavage in ADAMTS5 Deficient Mice; A Novel Etiology of Myxomatous Valve Disease

In fetal valve maturation the mechanisms by which the relatively homogeneous proteoglycan-rich extracellular matrix (ECM) of endocardial cushions is replaced by a specialized and stratified ECM found in mature valves are not understood. Therefore, we reasoned that uncovering proteases critical for ‘...

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Bibliografiset tiedot
Julkaisussa:Dev Biol
Päätekijät: Dupuis, Loren E., McCulloch, Daniel R., McGarity, Jessica D., Bahan, Alexandria, Wessels, Andy, Weber, Deidra, Diminich, A. Megan, Nelson, Courtney M., Apte, Suneel S., Kern, Christine B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435578/
https://ncbi.nlm.nih.gov/pubmed/21749862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.06.041
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