Complete release of (5′S)-8,5′-cyclo-2′-deoxyadenosine from dinucleotides, oligodeoxynucleotides and DNA, and direct comparison of its levels in cellular DNA with other oxidatively induced DNA lesions

8,5′-Cyclopurine-2′-deoxynucleosides in DNA are repaired by nucleotide-excision repair, and act as strong blocks to DNA polymerases, RNA polymerase II and transcription factor binding. Thus, it is important to accurately determine the level of these lesions in DNA. There is controversy in the litera...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Jaruga, Pawel, Theruvathu, Jacob, Dizdaroglu, Miral, Brooks, Philip J.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 2004
Pynciau:	NAR Methods Online
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh087
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