Complete release of (5′S)-8,5′-cyclo-2′-deoxyadenosine from dinucleotides, oligodeoxynucleotides and DNA, and direct comparison of its levels in cellular DNA with other oxidatively induced DNA lesions

8,5′-Cyclopurine-2′-deoxynucleosides in DNA are repaired by nucleotide-excision repair, and act as strong blocks to DNA polymerases, RNA polymerase II and transcription factor binding. Thus, it is important to accurately determine the level of these lesions in DNA. There is controversy in the litera...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Jaruga, Pawel, Theruvathu, Jacob, Dizdaroglu, Miral, Brooks, Philip J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2004
Schlagworte:	NAR Methods Online
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh087
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