Angiopoietin-like 4 Stimulates STAT3-mediated iNOS Expression and Enhances Angiogenesis to Accelerate Wound Healing in Diabetic Mice

Impaired wound healing is a major source of morbidity in diabetic patients. Poor outcome has, in part, been related to increased inflammation, poor angiogenesis, and deficiencies in extracellular matrix components. Despite the enormous impact of these chronic wounds, effective therapies are lacking....

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Vydáno v:Mol Ther
Hlavní autoři: Chong, Han Chung, Chan, Jeremy Soon Kiat, Goh, Chi Qin, Gounko, Natalia V, Luo, Baiwen, Wang, Xiaoling, Foo, Selin, Wong, Marcus Thien Chong, Choong, Cleo, Kersten, Sander, Tan, Nguan Soon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435481/
https://ncbi.nlm.nih.gov/pubmed/24903577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.102
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