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Promoter-binding and repression of PDGFRB by c-Myc are separable activities
The c-Myc transcription factor represses the mRNA expression of the platelet-derived growth factor receptor beta gene (PDGFRB). Using chromatin immunoprecipitation, we show that c-Myc binds to the proximal promoter of the PDGFRB gene in proliferating rat fibroblasts. Interestingly, mutant c-Myc prot...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443544/ https://ncbi.nlm.nih.gov/pubmed/15226411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh669 |
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