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Promoter-binding and repression of PDGFRB by c-Myc are separable activities

The c-Myc transcription factor represses the mRNA expression of the platelet-derived growth factor receptor beta gene (PDGFRB). Using chromatin immunoprecipitation, we show that c-Myc binds to the proximal promoter of the PDGFRB gene in proliferating rat fibroblasts. Interestingly, mutant c-Myc prot...

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Main Authors: Mao, Daniel Y. L., Barsyte-Lovejoy, Dalia, Ho, Cynthia S. W., Watson, John D., Stojanova, Angelina, Penn, Linda Z.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC443544/
https://ncbi.nlm.nih.gov/pubmed/15226411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh669
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