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The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter.

Increasing evidence supports an important biological role for Myc in the downregulation of specific gene transcription. Recent studies suggest that c-Myc may suppress promoter activity through proteins of the basal transcription machinery. We have previously reported that Myc protein, in combination...

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Udgivet i:Mol Cell Biol
Principais autores: Facchini, L M, Chen, S, Marhin, W W, Lear, J N, Penn, L Z
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.100
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