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Proposed three-dimensional structure for the cellular prion protein.

Prion diseases are a group of neurodegenerative disorders in humans and animals that seem to result from a conformational change in the prion protein (PrP). Utilizing data obtained by circular dichroism and infrared spectroscopy, computational studies predicted the three-dimensional structure of the...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Huang, Z, Gabriel, J M, Baldwin, M A, Fletterick, R J, Prusiner, S B, Cohen, F E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7913747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7139
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